李全梓

时间:2018-04-28 来源:未知  作者:超级管理


姓名: 李全梓
出生年月:1970年9月
籍贯: 江苏
专业: 林木分子生物学
专业职称: 研究员、博士生导师
电话; 15510717278
E-mail: liqz@caf.ac.cn
通讯地址: 北京市海淀区香山路中国林业科学研究院林木遗传育种国家重点实验室
邮编: 100091

学习简历:

1993年毕业于山东农业大学食品科学学院食品科学专业,获学士学位
1996年毕业于山东农业大学生命科学学院植物生理专业,获硕士学位
2002年毕业于山东农业大学生命科学学院植物学专业,获博士学位

工作经历:

1996年7月-2004年1月,山东农业大学生命科学学院,先后任助教,讲师和副教授
2004年1月-2005年7月,美国夏威夷大学海洋系,访问学者
2005年7月-2010年4月,美国北卡州立大学林学资源学院,博士后
2010年4月-2013年12月,美国北卡州立大学林学资源学院,助理研究员
2014年12月至今,中国林业科学院遗传育种国家重点实验室,研究员

学术兼职:

2013年5月-至今,Scientific Reports 编委

科研项目:

1.国家自然科学基金 “PtrSND1-A2 选择性剪接产物在木材发育过程中的功能解析及产生机制的初步探讨”(项目编号:31370593): 2014.1-2017.12
2.中国林业科学研究院国家重点实验室专项(项目编号:CAFYBB2016ZX001),2016.1-2018.12

学术成就:

发现了一个木材发育中调控次生壁加厚的基因选择性剪接产物并对其作用机制进行了探讨(PNAS, 109:14699-14704); 首次报道了一个小的RNA (miR397a) 控制木材中木质素的含量(PNAS, 110: 10848-10853); 揭示了蛋白复合体在木质素合成中扮演重要功能(PNAS, 108: 21253-21258)。
   
发表学术论文:

1. 发表文章


1.Li Q*, Song J, Peng S, Wang J, Qu G-Z, Sederoff RR, and Chiang VL* (2014) Plant biotechnology for lignocelllulosic biofuel production. Plant Biotechnol. J.  * (通讯作者,封面)。

2.Lin Y-C, Li W, Chen H, Li Q, Sun Y-H, Shi R, Lin C-Y, Wang JP, Chen H-C, Chuang L, Qu G-Z, Sederoff RR, and Chiang VL (2014). A simple high throughput xylem protoplast system for studying wood formation. Nat. Protocols,9:2194-2205.

3.Li W, Lin Y-C, Li Q, Shi R, Lin C-Y, Chen H, Chuang L, Qu G-Z, Sederoff RR, and Chiang VL (2014). A robust anti-transcription factor (TF) antibody-based chromatin immunoprecipitation (ChIP) protocol for studying TF direct targets in woody plants. Nat. Protocols,9:2180-2193.

4.Wang JP, Naik PP, Chen H-C, Shi R, Lin C-Y, Liu J, Shuford CM, Li Q, Williams CM, Muddiman DC, Ducoste JJ, Sederoff RR, and Chiang VL (2014). Complete proteomic based enzyme reaction and inhibition kinetics reveal how monolignol biosynthetic enzyme families affect metabolic-flux and lignin. Plant Cell. 26: 894-914.

5.Chen H-C, Song J, Wang JP, Lin Y-C, Ducoste JJ, Shuford CM, Liu J, Li Q, Shi R, Nepomuceno A, Isik F, Muddiman DC, Williams CM, Sederoff RR, and Chiang VL (2014). Systems biology of lignin biosynthesis in Populus trichocarpa: Heteromeric 4-coumaric acid: CoA ligase (4CL) protein complex formation, regulation and numerical modeling. Plant Cell. 26: 876-893.

6.Min D, Li Q, Chiang VL, Jameel H, Chang H, Lucia L (2014) The influence of lignin-carbohydrate complexes on the cellulase-mediated saccharification I: Transgenic black cottonwood (western balsam poplar, California poplar) P. trichcoarpa including the xylan down-regualted and the lignin down-regualted lines. Fuel, 119: 207-213.

7.Lu S,  Li Q (并列第一), Wei H, Chang M-J, Tunlaya-Anukit S, Kim H, Liu J, Song J, Sun Y-H, Yuan L, Yeh T-F, Peszlen I, Ralph J, Sederoff RR, Chiang VL (2013). Ptr-miR397a is a negative regulator of laccase genes affecting lignin content in Populus trichocarpa. PNAS USA 110: 10848-10853.

8.Lin Y-C, Li W, Sun Y-H, Kumari S, Wei H, Li Q, Tunlaya-Anukit T, Sederoff RR, Chiang VL (2103) SND1 transcription factor-directed quantitative functional hierarchical genetic regulatory network in wood formation in Populus trichocarpa. Plant Cell, 25: 4324-4341.

9.Loziuk PL, Wang JP, Li, Q, Sederoff RL, Chiang VL, Muddiman DC (2013) Understanding the role of proteolytic digestion on discovery and targeted proteomic measurement using liquid chromatograph tandem mass spectrometry and design of experiments. Journal of Proteome Research 12:5820-5829.

10.Shi R, Shuford CM, Wang JP, Sun Y-H, Yang Z, Chen H-C, Tunlaya-Anukit S, Li Q, Liu J, Muddiman DC, Sederoff RR, Chiang VL (2013) Regulation of phenylalanine ammonia-lyase (PAL) gene family in wood forming tissue of Populus trichocarpa. Planta 238:487-497.

11.Li Q*, Lin Y-C*, Sun Y-H, Song J, Chen H, Zhang X-H, Sederoff RR, Chiang VL (2012)  Splice variant of the SND1 transcription factor is a dominant negative of SND1 members and their regulation in Populus trichocarpa. PNAS USA 109:14699-14704 (*并列第一).

12.Chen H-C, Song J, Williams CM, Shuford CM, Liu J, Wang JP, Li Q, Shi R, Gokce E, Ducoste J, Muddiman DC, Sederoff RR, Chiang VL (2013) MonoligniMonolignol Pathway 4-Coumaric Acid:CoA Ligases in Populus trichocarpa: Novel Specificity, Metabolic Regulation, and Simulation of CoA Ligation Fluxes. Plant Physiology 161: 1501-1516.

13.Min D, Li, Q, Jameel H, Chiang VL, Chang H-M (2012) The cellulase-mediated saccharification on wood derived from transgenic low-lignin lines of black cottonwood (Populus trichocarpa). Appl Biochem Biotechnol 168: 947-955.

14.Liu J, Shi R, Li Q, Sederoff RR, Chiang VL (2012) A standard reaction condition and a single HPLC separation system are sufficient for estimation of monolignol biosynthesis pathway enzyme activities. Planta 236: 879-885.

15.Shuford CM, Li Q, Sun Y-H, Chen H-C, Wang JP, Shi R, Sederoff RR, Chiang VL, Muddiman DC (2012) Comprehensive quantification of monolignol-pathway enzymes in Populus trichocarpa by protein cleavage isotope dilution mass spectrometry. J. Proteome Research. 11:3390-3404.

16.Wang JP, Shuford CM,  Li Q, Song J, Lin Y-C, Sun Y-H, Chen H-C, Williams CM,  Muddiman DC, Sederoff RR, Chiang VL (2012) Functional Redundancy of the Two 5-Hydroxylases in Monolignol Biosynthesis of Populus trichocarpa:  LC-MS/MS Based Protein Quantification and Metabolic Flux Analysis. Planta 236: 795-808.

17.Chen H-C, Li Q, Shuford CM, Liu J, Muddiman DC, Sederoff RR, Chiang VL (2011) Membrane protein complexes catalyze both 4- and 3-hydroxylation of cinnamic acid derivatives in monolignol biosynthesis. PNAS USA. 108: 21253-21258.

18.Li Q*, Min D, Wang JP, Peszlen I, Horvath L, Horvath B, Nishimura Y, Jameel H,  Chang H-M, Chiang VL. (2011) Down-regulation of glycosyltransferase 8D genes in Populus trichocarpa caused reduced mechanical strength and xylan content in wood. Tree Physiology 31: 226-236 (* 通讯作者).

19.Zhou C, Li Q, Chiang VL, Lucia LA, Griffis DP (2011) Chemical and spatial differentiation of syringyl and guaiacyl lignin in poplar wood via time-of-flight secondary ion mass spectrometry. Analytical Chemistry 83:7020-7026.

20.Min D, Li Q, Jameel H, Chiang VL, Chang H-M (2011) Comparison of pretreatment protocols for cellulose-mediated saccharification of wood derived from transgenic low-xylan lines of cottonwood (P. trichocarpa). Biomass and Bioenergy 35: 3514-3521.

21.Shi R, Sun Y-H, Li Q et al (2010) Toward a systems approach for lignin biosynthesis in Populus trichocarpa: Transcript abundance and specificity of the monolignol biosynthetic genes. Plant and Cell Physiology 50:144-163.

2. 参与编著书:

1.Quanzi Li, Ting-Feng Yeh, Chenmin Yang, Jingyuan Song, Ronald R. Sederoff, and Vincent L. Chiang. 2015. Populus trichocarpa,in “Agrobacterium Protocols” . Methods in Mol. Biol. 1224: 257-363.

2.Guangyi Wang, Quanzi Li, Sanghwal Yoon. 2007. Biodiversity and biotechnological potentials of fungi from the marine environment. In: Rai, M. and S. K. Deshmukh (eds). Mycotechnology: Current trends and future prospects. I.K. International publishing House Pvt.Ltd., New Delhi. Pages 215-225

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